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Sometimes called the “whole-plant” or “entourage effect,” cannabis offers a complex biochemical matrix of many of its constituents working synergistically. There is much misinformation about the actual composition of some CBD-rich hemp products, however it actually contains many bioactive compounds that interplay to optimize health and wellness. This is what we call the “Hemptourage effect”.
The Biochemist: Miracle Cure? Alzheimer's disease Zuardi, A. W., Crippa, J. A., Hallak, J. E., Bhattacharyya, S., Atakan, Z., … & Guimarães, F. S. (2012). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation [Abstract]. Current Pharmaceutical Design, 18(32), 5,131-5,140. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22716160
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CBD oil refers to a natural botanical concentrate that is derived from the seeds and stalks of cannabis plants. This oil has a high concentration of cannabidiol, also known as CBD. Out of the identified cannabinoids in the cannabis plant, cannabidiol is the second most common after THC or tetrahydrocannabinol. However, unlike THC, cannabidiol is non-psychotropic. That means it’s use does not cause the euphoric high effect like traditional marijuana and THC products do.
Seizures arise when neurons become overactive at transmitting signals, firing more frequently than they should. “CBD will actually block the GPR55 receptor,” Whalley explains, and in doing so reduce how often the neuron fires. In a rodent model of epilepsy, animals engineered without GPR55 don’t respond to CBD, whereas those with the receptor do.
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WHY? Virginia SUPER SLOW SHIPPING In 2013, the American Journal of Medicine published a study that highlighted the impact of marijuana use on glucose, insulin and insulin resistance among U.S. adults. The study included 4,657 adult men and women from the National Health and Nutritional Examination Survey from 2005 to 2010. Of the participants, 579 were current marijuana users and 1,975 were past users. The researchers found that current marijuana use was associated with 16 percent lower fasting insulin levels. They also found significant associations between marijuana use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms. (17)
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But studying CBD is not easy: Scientists complain that laws and regulations put excessive constraints on their work. Although it doesn’t make users high, CBD (both the molecule and CBD-rich cannabis) is classified by the federal government as a Schedule 1 drug, which means they have high potential for abuse and no accepted medical use.
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Without distorting the science too much, you could say that human beings are “hard-wired” for weed. The endocannabinoid system runs deep and touches all of the major systems of the body. And that’s why weed can do so many things for us, from altering and regulating moods to stimulating appetites and reducing pain.
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For CBD itself, the evidence is even sparser. Abrams says the NAS report could identify only three small published randomized trials—the gold standard for medical research—that looked at just CBD. And for none of those conditions—anxiety, smoking cessation, and Parkinson’s disease—was the evidence strong enough for the NAS report to conclude that CBD clearly helps.
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25mg Caps, 1k Tincture, 2 Packs CBD Gum 5How to Add 12 Years (or More) to Your Life The use of medical marijuana continues to be an emotionally and politically charged issue. Although cannabis oil preparations have been used in medicine for millennia, the concern over the dangers of abuse led to the banning of the medicinal use of marijuana in the 1930s.
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