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Where to Purchase Hemp Oil Best Headphones Jump up ^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118. Research is beginning to show that CBD is different than other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. (2) Choose Login Red Kali $6.50 – $90.00 Abinoid Botanicals (6) *Disclaimer* Shop Lazarus Naturals Various breeds/strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC and are known to contain other non-psychotropic cannabinoids.[54] However it is only the amount of ∆9-THC that chemically gives a legal determination as to whether the plant material(s) used for the purposes of extracting CBD are considered hemp, or considered marijuana.[citation needed] 101 Photos USA/Global (English) Read More Worse, CBD is being produced without any regulation, resulting in products that vary widely in quality, said Marcel Bonn-Miller, an adjunct assistant professor of psychology in psychiatry at the University of Pennsylvania School of Medicine. 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